Also, a 47 year old female experienced a low hear rate, slurred speech, and dizziness, after applying her compounded pain cream containing five ingredients, including clonidine, a blood pressure medication. In a case reported last year, severe toxicity occurred in an 18-month-old child when his father's compounded ointment was used to treat a diaper rash. Pediatric patients have also experienced toxicity when the cream is applied to their skin intentionally for a skin condition. In one case, a child who became severely ill after applying his mom's compounded topical fibromyalgia medication to his body-gabapentin, ketamine, diclofenac, clonidine, nifedipine, bupivacaine, menthol, and cyclobenzaprine. (Fisher Scientific, HPLC grade) was used as organic modifier in. There have been cases of children ingesting or applying the creams, of adults intentionally abusing it, and of adults experiencing adverse effects with appropriate use. Hydrocortisone (HC) content compounded in the VersaPro base cream wasquantified using a. The Philadelphia Poison Control Center, one of our nation's 57 Poison Control Centers, has had 8 cases reported as a result of these products in the last 12 months, and no cases prior to that. In fact safety is likely to be more of an issue, even when used by the intended patient at the intended site. Consumers are charged per ingredient and there is really no proof that more ingredients make the product better.
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